emzski
Full Member
I shameless stole this from CD board, just thought I would share as its near the festive season! Thanks CD people!
DO NOT DRINK ALCOHOL IF YOU ARE KETOTIC!
Alcohol is a powerful inhibitor of gluconeogenesis. In fact, it forces part of the gluconeogenic metabolic process into reverse. This means that if all the glucose in the blood is being derived from gluconeogenesis then the consumption of alcohol will inevitably cause the blood glucose level to fall. Worse still, the alcohol also stops ketone body production, thus leaving the brain entirely without fuel.
A person who is ketotic is 100% reliant on gluconeogenesis to maintain adequate levels of glucose in the blood. If, under these circumstances alcohol is taken, the person will become disorientated and might lose consciousness, not just from the alcohol, but from low blood sugar. Needless to say, this could be very dangerous, and even fatal.
Alcohol does not have these effects if the glycogen stores in the liver are normal. Under these circumstances the blood glucose level in the blood is maintained by the breakdown of liver glycogen, a process that is not influenced by alcohol. If a person becomes confused under these circumstances it is due simply to the pharmacological effects of the alcohol!
DO NOT DRINK ALCOHOL IF YOU ARE KETOTIC!
Alcohol is a powerful inhibitor of gluconeogenesis. In fact, it forces part of the gluconeogenic metabolic process into reverse. This means that if all the glucose in the blood is being derived from gluconeogenesis then the consumption of alcohol will inevitably cause the blood glucose level to fall. Worse still, the alcohol also stops ketone body production, thus leaving the brain entirely without fuel.
A person who is ketotic is 100% reliant on gluconeogenesis to maintain adequate levels of glucose in the blood. If, under these circumstances alcohol is taken, the person will become disorientated and might lose consciousness, not just from the alcohol, but from low blood sugar. Needless to say, this could be very dangerous, and even fatal.
Alcohol does not have these effects if the glycogen stores in the liver are normal. Under these circumstances the blood glucose level in the blood is maintained by the breakdown of liver glycogen, a process that is not influenced by alcohol. If a person becomes confused under these circumstances it is due simply to the pharmacological effects of the alcohol!